The Methodist Episcopal Conference began construction on the building in 1925. A Guthrie nonprofit organization purchased the hospital in 1932 and named it Cimarron Valley Wesley Hospital.

In 1946, the Order of the Sisters of Benedict purchased the hospital and completed construction soon afterward.

St. Anthony Hospital , owned and operated by the Sisters of St. Francis of Maryville, Mo., bought the facility in 1964, renaming it Alvero Heights Hospital .

The name was changed to Logan County Memorial Hospital  in 1974.

The hospital was deeded to the county in 1977 and a replacement facility opened west of Guthrie in October, 1978.

In 1982, R&T Properties, a partnership of local businessmen Ray H. Riddle and Hal A. Treadwell, purchased the former Logan County Memorial Hospital and its four acres for an undisclosed price from the Logan County Hospital Trust Authority.

The five-story, 55,000-square-foot building, located at 19th and W Warner in Guthrie, was supposed to be remodeled into 50 to 70 one-bedroom and two-bedroom apartments but the project never got off the ground.